Dim str As String = "1,2,1,1,1,1,1,1,3,53,53,53,53,53,5,5,56,7,530"
For Each s As String In "1,2,1,1,1,1,1,1,3,53,53,53,53,53,5,5,56,7".Split(",")
Dim i As Integer = Array.IndexOf(str.Split(","),s)
If i > - 1 Then
str = str.Remove(i,s.Length)
End If
Next
MessageBox.Show(str.Replace(",",""))